E-ISSN 2577-5669
 

Review Article 


Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective

Alfred Maroyi.

Abstract
Background: Croton membranaceus is used as herbal medicine against benign prostate hyperplasia (BPH), cough, diabetes, diarrhoea, fever, flatulence, measles, nausea and urinary retention problems. Objective: The aim of this study was to review the medicinal, phytochemical, pharmacological and toxicological properties of C. membranaceus, a potentially useful medicinal plant species in West Africa.
Methods: Literature focusing on the botany, phytochemical, pharmacological and toxicological properties of C. membranaceus were obtained from scientific databases such as SCOPUS, ScienceDirect, Pubmed, SciFinder, Medline and Google Scholar. Pre-electronic literature such as books, book chapters, journal articles, conference papers and other scientific documents were obtained from the University library.
Results: Literature search revealed that the phytochemical compounds isolated from C. membranaceus include coumarin, diterpene, glutarimide alkaloid, glutarimide peptide, labdane diterpene and phytosterol. Pharmacological studies of C. membranaceus extracts and compounds isolated from the species revealed antibacterial, antifungal, antihyperglycaemic, antioxidant, antiplasmodial, antiproliferative, cytotoxicity, hypoglycaemic and prostate growth inhibitory effects of the species.
Conclusion: The phytochemical, pharmacological and toxicological studies done so far support the uses of C. membranaceus in traditional medicine. Therefore, future research on the species should focus on detailed in vitro, in vivo and clinical studies using compounds isolated from the species as well as crude extracts.

Key words: Croton membranaceus, ethnopharmacology, Euphorbiaceae, traditional medicine, West Africa


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Alfred Maroyi
on Google
on Google Scholar
Article Statistics
 Viewed: 3272
Downloaded: 330


How to Cite this Article
Pubmed Style

Maroyi A, . Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective. J Complement Med Res. 2018; 9(1): 24-33. doi:10.5455/jcmr.20180718123349


Web Style

Maroyi A, . Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective. http://www.jocmr.com/?mno=1256 [Access: February 15, 2020]. doi:10.5455/jcmr.20180718123349


AMA (American Medical Association) Style

Maroyi A, . Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective. J Complement Med Res. 2018; 9(1): 24-33. doi:10.5455/jcmr.20180718123349



Vancouver/ICMJE Style

Maroyi A, . Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective. J Complement Med Res. (2018), [cited February 15, 2020]; 9(1): 24-33. doi:10.5455/jcmr.20180718123349



Harvard Style

Maroyi, A. & (2018) Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective. J Complement Med Res, 9 (1), 24-33. doi:10.5455/jcmr.20180718123349



Turabian Style

Maroyi, Alfred, and . 2018. Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective. Journal of Complementary Medicine Research, 9 (1), 24-33. doi:10.5455/jcmr.20180718123349



Chicago Style

Maroyi, Alfred, and . "Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective." Journal of Complementary Medicine Research 9 (2018), 24-33. doi:10.5455/jcmr.20180718123349



MLA (The Modern Language Association) Style

Maroyi, Alfred, and . "Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective." Journal of Complementary Medicine Research 9.1 (2018), 24-33. Print. doi:10.5455/jcmr.20180718123349



APA (American Psychological Association) Style

Maroyi, A. & (2018) Review of Croton membranaceus Műll. Arg.: phytochemical, pharmacological and toxicological perspective. Journal of Complementary Medicine Research, 9 (1), 24-33. doi:10.5455/jcmr.20180718123349