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Review Article 


Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review

Janmejaya Samal.

Cited by (1)

Abstract
Background: Tuberculosis is a global public health crisis. 25% of world’s TB cases are found in India. Ayurveda, an ancient medical science may offer some solution to this problem hence a systematic review was carried out to assess the role of Ayurveda for the management of Tuberculosis. Methodology: A systematic review was carried out using published literature obtained through “PUBMED” till April 2015. The key words used for literature search include “Ayurveda, role and Tuberculosis”. Results and Discussion: It was observed that a couple of single and compound drugs have been used for the management of tuberculosis. However none of the studies could reflect the true anti-tubercular activities of any drug, both single and compound. Two of the studies revealed in vitro anti-tubercular properties of some herbs which can potentially be brought in to the realm of clinical trial to test their efficacy in human subject. Most of these Ayurvedic therapeutic preparations studied at different clinical settings primarily reflected their adjunct properties for the management of Tuberculosis. These studies revealed that Ayurvedic therapeutics were able to reduce associated symptoms and the adverse drug effects of ATDs (Antitubercular Drugs). Furthermore some of the preparations showed potential hepato-protective properties that can be simultaneously administered with ATDs. Conclusion: Distressingly research on the role of Ayurveda in the management of Tuberculosis is very scanty and mostly limited to adjunct or supportive therapy. Being a global public health crisis, it is highly recommended to carry out clinical trials on Tuberculosis patients by using Ayurvedic drugs and therapeutic regimens.

Key words: Adjunct therapy, Ayurveda, Herbal Drugs, Rajayakshma, Tuberculosis


 
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REFERENCES
1. Murray CJ, Lopez AD. The global burden of disease: A comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020: Summary. W 74 96GL-1/1996. Geneva, Switzerland: WHO; 1996.
2. Udwadia ZF. Tuberculosis in India: Ancient enemy just gets stronger. BMJ 2015;350:h1080. [DOI via Crossref]    [DOI via Crossref]   
3. TBC India. Directorate General of Health Services, Ministry of Health and Family Welfare, Government of India. Available from: http://www.tbcindia.nic.in. [Last accessed on 2015 Apr 15].
4. Uplekar M, Juvekar S, Morankar S, Rangan S, Nunn P. Tuberculosis patients and practitioners in private clinics in India. Int J Tuberc Lung Dis 1998;2:324-9.
5. Dholakia Y, Quazi Z, Mistry N. Drug-resistant tuberculosis: Study of clinical practices of chest physicians, Maharashtra, India. Lung India 2012;29:30-4. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
6. Charak A. In: Shastri K, Chaturvedi GN, Vidyatini Hindi Commentary, editors. Charak Samhita. Part I and II. Varanasi: Chaukhamba Sanskrit Series; 1969.
7. Vyas P, Chandola HM, Ghanchi F, Ranthem S. Clinical evaluation of Rasayana compound as an adjuvant in the management of tuberculosis with anti-Koch�s treatment. Ayu 2012;33:38-43. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
8. Dornala SN, Dornala SS. Clinical efficacy of Bhringarajasava as Naimittika Rasayana in Rajayakshma with special reference to pulmonary tuberculosis. Ayu 2012;33:523-9. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
9. Debnath PK, Chattopadhyay J, Mitra A, Adhikari A, Alam MS, Bandopadhyay SK, et al. Adjunct therapy of Ayurvedic medicine with anti tubercular drugs on the therapeutic management of pulmonary tuberculosis. J Ayurveda Integr Med 2012;3:141-9. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
10. Sharma YK, Singh H, Mehra BL. Hepatoprotective effects of few Ayurvedic herbs in patients receiving antituberculus treatment. Indian J Tradit Knowl 2004;3:391-6.
11. Kumar JK, Devi Prasad AG, Chaturvedi V. Phytochemical screening of five medicinal legumes and their evaluation for in vitro anti-tubercular activity. Ayu 2014;35:98-102. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
12. Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, et al. Anti-tuberculosis activity of selected medicinal plants against multidrug resistant Mycobacterium tuberculosis isolates. Indian J Med Res 2010;131:809-13.
13. Singh RH. Rasāyanā and Vajikarana (promotive therapy). In: Sharma PV, editor. History of Medicine in India. New Delhi, India: Indian National Science Academy; 1992. p. 242-54.
14. Byrd RP. Malnutrition and pulmonary tuberculosis. Clin Infect Dis 2002;35:633-4.
15. Askgaard DS, Wilcke T, D�ssing M. Hepatotoxicity caused by the combined action of isoniazid and rifampicin. Thorax 1995;50:213-4. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
16. Khanna BK. Hepatitis during INH, Pyrazinamide and rifampicin therapy. Indian J Tuberc 1983;30:104.
17. Kuete V. Potential of Cameroonian plants and derived products against microbial infections: A review. Planta Med 2010;76:1479-91. [DOI via Crossref]    [Pubmed]   
18. Kuete V, Efferth T. Cameroonian medicinal plants: Pharmacology and derived natural products. Front Pharmacol 2010;1:123. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
19. Trease GE, Evans WC. The Pharmacognosy. 11th ed. London: Brailliar Tiride Land Mac Millian Publishers; 1989. p. 710-84.
20. Ministry of Health and Family Welfare. National Health System Resource Center-National Rural Health Mission, Mainstreaming of AYUSH and Revitalization of Local Health Traditions Under NRHM, An Appraisal of the Annual State Programme Implementation Plans 2007-2010 and Mapping of Technical Assistance Needs. New Delhi: Government of India.
21. Samal J. Role of AYUSH Workforces, Therapeutics and principles in health care delivery with special reference to National Rural Health Mission. Ayu 2015;36:5-9. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   

This Article Cited By the following articles

Medicinal plants used in the treatment of tuberculosis - Ethnobotanical and ethnopharmacological approaches
Biotechnology Advances 2017; (): .

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Pubmed Style

Janmejaya Samal. Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review. J Complement Med Res. 2016; 5(1): 86-91. doi:10.5455/jice.20151107020621


Web Style

Janmejaya Samal. Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review. http://www.jocmr.com/?mno=204729 [Access: November 15, 2018]. doi:10.5455/jice.20151107020621


AMA (American Medical Association) Style

Janmejaya Samal. Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review. J Complement Med Res. 2016; 5(1): 86-91. doi:10.5455/jice.20151107020621



Vancouver/ICMJE Style

Janmejaya Samal. Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review. J Complement Med Res. (2016), [cited November 15, 2018]; 5(1): 86-91. doi:10.5455/jice.20151107020621



Harvard Style

Janmejaya Samal (2016) Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review. J Complement Med Res, 5 (1), 86-91. doi:10.5455/jice.20151107020621



Turabian Style

Janmejaya Samal. 2016. Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review. Journal of Complementary Medicine Research, 5 (1), 86-91. doi:10.5455/jice.20151107020621



Chicago Style

Janmejaya Samal. "Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review." Journal of Complementary Medicine Research 5 (2016), 86-91. doi:10.5455/jice.20151107020621



MLA (The Modern Language Association) Style

Janmejaya Samal. "Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review." Journal of Complementary Medicine Research 5.1 (2016), 86-91. Print. doi:10.5455/jice.20151107020621



APA (American Psychological Association) Style

Janmejaya Samal (2016) Ayurvedic management of Pulmonary Tuberculosis (PTB): A systematic review. Journal of Complementary Medicine Research, 5 (1), 86-91. doi:10.5455/jice.20151107020621





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