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Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review

Siva Kumar Tekuri, Sivarama Krishana Pasupuleti, Kranthi Kumar Konidala, Neeraja Pabbaraju.

Abstract
Polyalthia cerasoides (Roxb.) Bedd. is also known as Guatteria cerasoides or Uvaria cerasoides belonging to the family of Annonaceae. P. cerasoides is used in traditional and folklore system of medicine extensively across Asian and African countries for its various pharmacological properties as treatment of toothaches, fever and combat stress. An exhaustive bibliographic search related to P. cerasoides, noticed that, a large number of bioactive compounds, such as aporphine alkaloids, sequiterpenes, diterpenes, Phenolics and Isoquinolene compounds enriched the stem bark and roots. The scientific ethnopharmocological studies proved that it possesses a wide range of biological activities such as anti inflammatory, antioxidant, antidiabetic, antimicrobial, hepatoprotective, anticancerous, analgesic studies and antistress activities. Scientific investigation on isolated bioactive components (Cerasoidine, Polyalthidin, laudanidine, codamine, bidebiline E etc.,) exhibits the antimalarial activity against Plasmodium falciparum, antimycobacterial activity against Mycobacterium tuberculosis and anticancer activities. Its efficacy on diseases proved the future usefulness of different species of P. cerasoides. The toxicity studies reveal its non-toxic effect even at larger doses. This review provides the scope of phytochemical, pharmacological, medicinal and non-medicinal uses of P. cerasoides. Further extensive investigation on P. cerasoides for its therapeutic potential related to folklore claims and shed the light on its unexplored potentialities.

Key words: Polyalthia cerasodes; bioactive compounds; pharmacological activities; folklore


 
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Pubmed Style

Tekuri SK, Pasupuleti SK, Konidala KK, Pabbaraju N, . Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review. J Complement Med Res. 2019; 10(1): 38-49. doi:10.5455/jcmr.20190108065022


Web Style

Tekuri SK, Pasupuleti SK, Konidala KK, Pabbaraju N, . Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review. http://www.jocmr.com/?mno=25006 [Access: April 26, 2019]. doi:10.5455/jcmr.20190108065022


AMA (American Medical Association) Style

Tekuri SK, Pasupuleti SK, Konidala KK, Pabbaraju N, . Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review. J Complement Med Res. 2019; 10(1): 38-49. doi:10.5455/jcmr.20190108065022



Vancouver/ICMJE Style

Tekuri SK, Pasupuleti SK, Konidala KK, Pabbaraju N, . Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review. J Complement Med Res. (2019), [cited April 26, 2019]; 10(1): 38-49. doi:10.5455/jcmr.20190108065022



Harvard Style

Tekuri, S. K., Pasupuleti, S. K., Konidala, K. K., Pabbaraju, N. & (2019) Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review. J Complement Med Res, 10 (1), 38-49. doi:10.5455/jcmr.20190108065022



Turabian Style

Tekuri, Siva Kumar, Sivarama Krishana Pasupuleti, Kranthi Kumar Konidala, Neeraja Pabbaraju, and . 2019. Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review. Journal of Complementary Medicine Research, 10 (1), 38-49. doi:10.5455/jcmr.20190108065022



Chicago Style

Tekuri, Siva Kumar, Sivarama Krishana Pasupuleti, Kranthi Kumar Konidala, Neeraja Pabbaraju, and . "Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review." Journal of Complementary Medicine Research 10 (2019), 38-49. doi:10.5455/jcmr.20190108065022



MLA (The Modern Language Association) Style

Tekuri, Siva Kumar, Sivarama Krishana Pasupuleti, Kranthi Kumar Konidala, Neeraja Pabbaraju, and . "Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review." Journal of Complementary Medicine Research 10.1 (2019), 38-49. Print. doi:10.5455/jcmr.20190108065022



APA (American Psychological Association) Style

Tekuri, S. K., Pasupuleti, S. K., Konidala, K. K., Pabbaraju, N. & (2019) Pharmacological Effects of Polyalthia cerasoides (Roxb.) Bedd.: a brief Review. Journal of Complementary Medicine Research, 10 (1), 38-49. doi:10.5455/jcmr.20190108065022





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