Emotions control our thinking, behavior and actions. Many people were never taught how to express their emotions, this leads to Depression. This study aims to assess the effectiveness of Rational Emotive Behavior Therapy on level of depression. Quantitative research approach, Pre experimental one group pretest posttestdesign was utilized. By using Non probability convenience sampling technique 60 samples were selected and the samples who met the inclusion criteria, with the help of Beck depression inventory pretest & posttest level of depression were assessed. The results of the study with regard to effectiveness of rational emotive behavior therapy reveals that the pretest mean is 20.01 and standard deviation is 1.18, whereas posttest mean is 11.76 and standard deviation is 0.63. The calculated value of z- test is 58.92 and tabulated value is 1.96.The study concludes that rational emotive behavior therapy is an effective psychotherapeutic approach in reducing the level of depression among depressive patients.