The term TORCH complex or TORCHes infection refers to the congenital Infections of toxoplasmosis, others (Syphilis, Hepatitis B), rubella, Cytomegalovirus (CMV), and herpes simplex. These are caused by Toxoplasma gondii, Treponema pallidum, Hepatitis B virus, Rubella virus, cytomegalovirus, and herpes virus simplex (HSV) viruses respectively. Other pathogens associated with congenital infections include human immunodeficiency virus (HIV), parvovirus, and varicella virus. It is the intrauterine transmission of these infections to the fetus which produces multiple symptoms when the child is born. Maternal risk factors include lapsed immunizations, sexually transmitted infections, and animal exposures during pregnancy. The timing of maternal infection if a key epidemiologic factor because fetal damage usually depends on the gestational age. With the exception of HSV, infections during the first trimester have the worst outcome. PROBLEM STATEMENT A study to evaluate the effectiveness of structured teaching programme on knowledge regarding prevention of TORCH Complex during pregnancy among antenatal mothers in selected Community Health Centers (CHCs) of Kanpur. OBJECTIVES 1. To assess the pre-test level of knowledge regarding prevention of TORCH Complex during pregnancy among antenatal mothers in selected Community Health Centers (CHCs) of Kanpur. 2. To determine the effectiveness of structured teaching programme on knowledge regarding prevention of TORCH Complex during pregnancy among antenatal mothers. 3. To find out the association between pre-test knowledge regarding prevention of TORCH Complex during pregnancy among antenatal mothers with their selected demographic variables. METHOD The study was quasi-experimental research design.Setting of the study was conducted at selected Comminity Health Centers (CHCs) of Kanpur. RESULT The study showed that among 60 antenatal mothers, the result of pretest knowledge consist of level 13(21.67%) Inadequate knowledge, 47(78.34) Moderate knowledge and 0(0%) adequate knowledge. The result of the post-test knowledge consist of level 0(0%) Inadequate knowledge, 48(80%) Moderate knowledge and 12(20%) Adequate knowledge. Increase percentage of knowledge showed improvement in the knowledge regarding prevention of TORCH Complex among antenatal mothers. CONCLUSION The result of the study showed that there is significant association between age, religion, monthly income, types of family, educational status, gestational weeks, area of residence and food habits of mothers.