Root canal irrigation is considered an important procedure of root canal treatment as it involves the healing of periapical tissues after treatment . In root canal irrigation , the motto is prevention of reinfection. Standard irrigation techniques are using common irrigants like NaOCl , chlorhexidine , EDTA etc but in this study , advanced root canal irrigants are reviewed . The newer irrigants like tetraclean , MTAD , ECA ( Electronically activated solutions) , ozonated water , herbal induced irrigants can all serve as an adjunct to the commonly used root canal irrigants. Potential newer/advanced irrigants serve as a substitute for traditional endodontic irrigants. With the recent studies performed and available literature , even though none of the irrigants fully satisfy the requirements of an ideal root canal treatment they can all be used as an adjunct over the commonly used irrigants.