Loss of tooth affects mastication, speech, esthetics and impairs the quality of life. Dental caries is a common oral health problem affecting people globally. A knowledge of etiology of tooth loss may help us to take preventive measures and limit future extractions of teeth. The aim of the study was to investigate the age and gender distribution of patients undergoing extraction of teeth for dental caries at Saveetha Dental College and Hospitals. In this retrospective cross-sectional study, digital case records of all patients who underwent extractions for dental caries in Saveetha Dental College and hospital from June 2019 to March 2020 were reviewed. Demographic details of patients were recorded from digital case records. Retrieved data was analysed using IBM SPSS Software Version 23.0. Descriptive statistics and tests of association of categorical variables by Chi square tests were done and results were obtained. P value < 0.05 was considered statistically significant. Among 6808 patients who underwent extraction of teeth for dental caries in Saveetha Dental College, more extraction were done among patients in the age group of 31-40 (22.31%). Extractions for dental caries in males (53.98%) were predominantly higher compared to females (46.02%). On comparing the association between age and gender, the results were statistically significant. (Pearson’s Chi square test, p<0.001). Within the limits of the present study, it can be concluded that the prevalence of tooth loss was more in the age group of 31-40 years with male predilection. This study will create awareness among people regarding the cause and reasons behind tooth loss, thereby preventing it at an early stage.