Objective: The first objective of our meta-analysis study and systematic review has been the evaluation of the patients’ treatment outcomes with immediate fibula transfer. Hence the second purpose of this study was the evaluation of the treatment outcomes of hybrid implants. Methods: Using electronic databases like Cochrane Library, PubMed, ISI as well as Embase, we systematically reviewed the related studies conducted from 2015 to August 2020. The mesh terms were used to search for keywords—two reviewers after reading the full text and abstract, blinding, and independently extracted data. Meta-analysis was performed using Stata V16 software, funnel plots and forest plots were shown for the results. Results: A total of 124 (Immediate fibula transfer) and 114 (hybrid implant) topics, abstracts, as well as full text have been obtained in our electronic searches. Finally, four 124 (Immediate fibula transfer) and five (hybrid implant) investigations matched fulfilled our inclusion criteria for doing a systematic review. The total failure rate and Flap complications were 7.14% and 12.8%, respectively. The survival rate of immediate reconstruction by fibula transfer was RR, 0.03 95% CI -0.01, 0.06. P = 0.11. Conclusion: Jaw’s immediate reconstruction, fibula flap, was affected, and its survival is high. Also, the success rate of hybrid implants has been reported high.