Diabetes is a chronic metabolic disease that affects millions of individuals across the world and has a significant impact on human existence. Diabetes mellitus is a well-known endocrine condition that is becoming increasingly prevalent in India. In this study, using suitable animal models, researchers evaluated an extract produced from Gymnema Silvestre leaves, Momordica charantia fruit juice extract, and Synzigium cumini seeds extract for pharmacological activities such as antihyperglycemic and antidiabetic activity. Following that, nanoparticles were created and characterised utilising a variety of techniques. Following that, a polyherbal tablet was developed and tested in a variety of pre and post compression conditions. Finally, the pharmacokinetic characteristics of a madefrom-scratch polyherbal tablet was compared to a commercially available formulation.