Introduction: Children with chronic kidney disease undergoing hemodialysis are facing many problems, one of the most important problems of these patients is sleep disorders, which affects the morbidity and mortality of these people. Therefore, this study was conducted with the aim of comparing the amount of sleep disorder in children with chronic kidney disease and healthy children of the same ages. Materials and methods: This study is a case-control type. Children with chronic kidney disease and healthy children referred to the General Clinic of Hazrat Ali Asghar Hospital in year 2022 were included in the study. Sampling was done by easily available methods. 50 children in the case group and 50 children in the control group were examined. Children's sleep habits questionnaire was used to determine sleep disorders. Also, the demographic and clinical characteristics of the patient, including age, sex, BMI, and the researcher's checklist were recorded. Then the data of two groups were recorded and analyzed using SPSS software version 22. The p value in this study was considered less than 0.05. Results: In this study, 60 cases of the all samples (60%) were girls (30 in the case group and 30 in the control group) and the average age in both groups was 8.79±3.68. The two groups were not significantly different in terms of age, gender and number of years of education. The number of family members in the samples was between 3-9. The severity of chronic renal failure in the group of patients was between 3-5 with an average of 4.32 ± 0.87. 48 cases (96%) of children with CKD had sleep disorder, which number was equal to 32 cases (64%) in the control group. Comparison of subgroup scores in the sleep disorder questionnaire, including sleep time, sleep behavior, night waking, waking up, daytime sleepiness, and other cases, all showed that the scores of subgroups were higher in patients with CKD. Also, in this study, parents of chronic kidney disease patients considered sleep disorder in their children to be less of a problem than parents of healthy children, and this was the case in all subgroups and the total score. Conclusion: The results of this study showed that the prevalence of sleep disorders in children with chronic kidney disease is higher than in healthy children.