Medicinal plants have long been recognized as a source of bioactive agents, and they continue to be a valuable resource for developing new drug prospects. In Mindanao, many indigenous plants are still used in treating multiple health issues.One of them is Anodendron borneense (King & Gamble) D.J. Middleton, locallyknown as “Lunas tag-uli” or “himag”. Even with numerous ethnomedicinal uses ofthis species, its pharmacological properties still need evaluation. This study's primary objective was to understand some of the basis of the ethnomedicinalclaims by assessing the extract's antioxidant, antibacterial, and antifungalproperties, including a qualitative identification of bioactive compounds. Theresults showed growth inhibition against the positive bacteria Staphylococcus aureus and two fungal organisms - Candida albicans and Aspergillus niger.Phytochemical screening revealed abundant flavonoids and saponins and amoderate level of steroids but showed weak antioxidant activity. Twenty-five (25)bioactive compounds were reported in many studies to have varied pharmacological activities and importance. The research findings may highlightthe significance of the ethnomedicinal value of A. borneense and as a potentialsource of compounds with medicinal importance