Aim: To evaluate the microbiological quality and toxicity potential of commonly consumed oral herbal liquid preparations (Agbo) in some areas of Abuja, Nigeria. Methods: Herbal liquid preparations (Agbo) were collected from different locations of the Municipal Area of Abuja, Nigeria. Samples were analyzed for elemental content using a flame atomic absorption spectrophotometer. Microbiological quality assessment was determined by suitability and sterility testing, and the contaminants were characterized to genera level. A portion of the samples (20 %) were subjected to in vitro hemolysis testing using mammalian (goat) blood. Results: Minerals like chromium and manganese were found to be absent, while calcium, copper, iron, potassium, sodium, magnesium, lead (Pb), and zinc were detected at variable concentrations. Eleven percent ofthe samples contained Pb above WHO permissible limit. Sixty percent of the samples were found to be contaminated with microbes like Bacillus, Staphylococci, Escherichia coli, Pseudomonas, Salmonella, and Proteus, besides, fungi like Microsporum, Rhizopus, Aspergillus, and yeast were also found. In vitro hemolysis showed that half of the samples had hemolysis values greater than 50%. One of the samples had a considerably high value (100 %) revealing the substantial extent of red blood cell lysis due to these Agbo preparations. Conclusion: This study is a pointer to the potential harm that the consumption of Agbo can cause as it is purported to be safe and regularly consumed in liberal amounts.