The global prevalence of dental caries is very high and reaches upto 95% in developing nations. Dental caries is considered a multifactorial and dynamic microbiological disease that causes destruction of the teeth. The aim of this study was to evaluate the teeth and gender distribution of dental caries in patients between the age groups of 18 to 25 years. The data of patients of 18 to 25 years of age who reported to Saveetha dental college between June 2019 to March 2020 were collected and analysed. The results were tabulated in the excel sheet. The data analysis was done using the SPSS software (IBM corp. Version 20.0). A total of 7577 cases were evaluated and tabulated. The total number of teeth with caries were 16630. Caries were found more in mandibular arch (56.16%) than in maxillary arch (43.83%). Molars had the highest number of dental caries compared to premolars and the anterior teeth in both maxillary and mandibular arches. Number of caries was higher in males than females and this association was statistically significant (P value- 0.002; Chi square test). It can be concluded from the study that the dental caries was more prevalent among the male gender and present more in the mandibular arch.