Introduction: Rose (rosa canina) is one of the flowers that are much in demand by the community because besides being an ornamental flower it can also be used as a cosmetic base material. Metallic silver (Ag) is a resilient transition element that has been utilised for a long time in jewellery, coinage, and silverware due to its scarcity (ranking 67th in abundance among the elements) and alluring white metallic brilliance. Aim: To study the anticariogenic activity of Rose Jasmine formulation mediated silver nanoparticles. Materials and methods: Muller hinton agar were utilised to identify the zone of inhibition at different concentrations of the prepared extract mediated with silver nanoparticles. Results: It showed that the prepared extract had an average of zone of inhibition at 100ul of the prepared extract. Conclusion: The prepared extract mediated silver nanoparticles had good anticariogenic activity at 100ul concentration.