Online ISSN: 2577-5669

Antioxidant and Antidiabetic Activity of Ethanolic Extract of Terminalia Chebula

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S. Kesava priya , T. Lakshmi, Anitha Roy , S. Rajeshkumar
» doi: 10.5455/jcmr.2022.13.02.16

Abstract

Primary antioxidants directly scavenge free radicals, while secondary antioxidants indirectly prevent the development of free radicals through Fenton’s reaction. Antioxidant activity is characterised as “a limitation of the oxidation of proteins, lipids, DNA, or other molecules that occurs by blocking the propagation stage in oxidative chain reactions.”Phytochemical screening of both extracts indicated the presence of phenolic compounds, flavonoids, saponins, tannins, and steroids, which might contribute to the antidiabetic activity. The research is needed to find whether the ethanolic extract of terminalia chebula has antioxidant and antidiabetic activity. The research also fulfils the deficiency of work on comparing its antioxidant and antidiabetic activity of terminalia chebula to compare with its standards.The aim of the research is to find the antidiabetic and antioxidant activity of ethanolic extract of terminalia chebula. The methodology adopted in this study was DPPH assay. For antidiabetic activity a total of 5 concentrations of ethanolic extract of terminalia chebula was prepared and compared with the standard and for antioxidant activity a total of 5 concentrations was compared to the standard. From the results both shows when the concentration increases the percentage of inhibition also increases when compared to standard in antioxidant activity and antidiabetic activity when concentration increases the percentage of inhibition also increases when compared to standard.

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