Background: Inflammatory bowel diseases (IBDs) are a group of diseases characterized by the presence of chronic inflammation in the absence of an infectious etiology. The main diseasesare Crohn’s disease (CD) and ulcerative colitis (UC). Aim:This study aimedto assess inflammatory bowel disease patient's needs and problems from a nursing perspective. Design: A descriptive exploratory research design was used. Setting:This study was conducted inoutpatient clinics, gastroenterology clinic, Medical Hospital, Ain Shams University Hospital. Subjects:A purposive sample of (130) adult patients from both sex attending to outpatient clinics. Tools:Two tools were used for data collection. Tool I: Patient’s structured interview questionnaire: which include (a) Patient’sdemographic characteristics, (b) Patient’s Medical Data. Tool II: Patients needs and problems assessmentquestionnaire: which include (a) Patient's knowledge regarding inflammatory bowel disease. (b) Patient's needs regarding inflammatory bowel disease. Results: The study concluded that (54.6%) of the studied patients with IBD had the highest level of physical, psychologicaland socialneeds. Also, more than half of the studied patients with IBD had the lowest level of functional needs. Additionally, more than half of the patients with IBD had the highest level of needs. Conclusion: The study findings reported thatmore than half of the studied patients with IBD had the highest level of needs. Additionally,there was a highly statistically positive correlation between total score of physical, psychological, social and functional needs among patients with inflammatory bowel disease. Recommendation: Health education programs should be applied to increase the patients' knowledge regarding lifestyle changes and provide possible solutions to the factors that may affect the changes of their lifestyle.