Pharmacovigilance is well known that the World Health Organization (WHO) launched the initiative to report any negative drug reactions.Theterm"pharmacovigilance"referstothescienceandpracticesinvolvedinidentifying,evaluating, comprehending, and averting drug side effects or other potential issues related todrugs. Eco pharmacovigilance (EPV) can be characterized as the process of identifying, assessing,determining the cause and effect of pharmaceuticals in the environment, as well as preventingtheirnegativeeffects. Ecopharmacovigilance is the study of all drug-related side effects on humans and other animalsas well as toxic reactions in the ecosystem. The use of drugs is growing daily in the veterinary and human populations. One report states that antimicrobials are used in 100,000 tonnes world wide.Monitoring the side effects of pharmaceuticals is the goal of both PV and EPV. PV is done on patients, whileEPVis done in the environment. It is far more difficult to prevent a pharmaceutical residue from human usage in the environment, which is an inevitable result of patient drug use. It can be addressed by efficient sewage treatment, which could stop serious environmental degradation. One of the major global challenges is that any observed ecological trends or negative environmental effects will initially be linked to a specific one. The antiviral medication oseltamivir, sometimes known as Tamiflu, has also been shown instudies to havelittle chance of harming the environmentdespite being widely used due to thebirdflupandemic.