Background: Non-specific mechanical neck dysfunction is one of the common musculoskeletal disorders leading to personal suffering, Sick leave and social cost. Purpose: To evaluate the extracorporeal shockwave therapy (ESWT) effect on non-specific mechanical neck pain. Methods: Thirty adult female participants with non-specific neck pain were engaged in this study. Their age ranged between 18-25 years with normal BMI (18-25 kg/cm2). They were distributed randomly into study and control groups each one contained 15 participants. The study group received ESWT and traditional treatment. While only traditional treatment was given to the control group. The treatment program was scheduled for 1 session per week for 4 weeks. Each participant was assessed pre and after 4 weeks of treatment to measure pain, neck ROM and neck function by VAS, CROM and NDI, respectively. Results: The result showed a significant difference between the mean values of all variables measured in the two groups before and after treatment as P value <0.05. While after treatment mean values in all variables of the two groups showed a non-significant difference, as P value >0.05 except in CROM flexion, extension, LT lateral bending and RT rotation. Conclusion: ESWT and traditional treatment have positive effect on neck dysfunction and they nearly have the same effect on Neck Pain, ROM and functional level.