Nocturnal enuresis (NE) and obsessive compulsive disorder (OCD) can profoundly affect psychological and social health, and their co occurrence presents complex therapeutic challenges. This case study f ocuses on Mr. R, a 21 year old with lifelong NE and adolescent diagnosed OCD, exploring the psychosocial factors and family dynamics influencing his conditions. Despite interventions like psychoeducation and cognitive behavioral therapy, Mr. R's significan t anxiety persists, tied to symptoms of both disorders. This case illustrates the difficulties in treating comorbid NE and OCD, underscoring the necessity for integrated treatment approaches that consider both psychological impacts and physiological manife stations. The study also emphasizes the importance of supportive family dynamics in managing chronic health issues, suggesting a need for further research into specific interventions that effectively target the nexus of somatic and mental health symptoms.