Increasing the number of human infected by viruses around the world make some problems to the health care systems. Dealing with patients thinks is an important manner. The present work idea is to use cold atmospheric plasma in study the effect on the coronavirus. Samples of nasal had been used to the test. The samples were of people accident by the virus for certain time of examinations. Cold atmospheric plasma system used with argon as discharge gas in the experiments. PCR test made to all samples before and after exposure to plasma. Results show that the PCR test was negative after 6 minutes of exposure to the cold atmospheric plasma. Results leads to find a new fast novel method to sterilization or hygiene of patient things in simple way.