The article discusses the features of surgical prevention of thrombosis in modern conditions. The author notes that due to the high risk of death, thrombosis that occurs during surgical interventions of various types have a significant impact on the quality of medical care in the surgical environment. Accordingly, it is very important to determine the risk of postoperative venous thromboembolism and evaluate the features of its prevention. A particular risk is the development of venous thromboembolism (VTE), which combines deep veinthrombosis (DVT) and pulmonary embolism (PE). Experts call it a multifactorial and serious disease. Accordingly, it is very important to study theoretical and practical approaches to the organization of prevention of thrombosis in particular and VTE in general in surgical practice, since even a competently and effectively performed operation can cause the death of a patient. Accordingly, the purpose of this work is to identify the features of surgical prevention of thrombosis and VTE in modern conditions.