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Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri.

Cited by (7)

Abstract
Aim: Four medicinal plants of Trigonella foenum-graecum, Zhumeria majdae, Achillea wilhelsii and Viola tricolor are traditionally used in Iran as analgesic and for treatment of inflammatory disorders. At the present atudy, the antinociceptive and anti-inflammatory effects of these plants have been studied.
Methods: The antinociceptive and anti-inflammatory activity of methanol extracts of tested plants were evaluated using hot-plate and carrageenan-induced edema methods respectively. The plant extracts were studied by i.p administration at three doses of 100, 200 and 400mg/kg.
Results: In the hot-plate test, the extracts of T. foeunm-graecum (100 mg/kg) and Z. majdae (200 and 400m g/kg) significantly increased the tolerance to pain in female albino mice in comparison to control. The administration of T. foenum-graecum at doses of 100 and 200mg/kg and V. tricolor (400mg/kg) significantly reduced the paw edema in male rat which measured in all the times of observation after carrageenan administration in comparison to control and reference (Ibuprofen, 400mg/kg).
Conclusions: The present work comparatively demonstrated considerable antinociceptive and anti inflammatory effect of all of the tested plants especially T. foeunm-graecum. The results here confirm traditional uses of T. foeunm-graecum both as analgesic or anti inflammatory agents.

Key words: Antinociceptive, Hot-Plate, Carrageenan-Induced edema, Anti inflammatory, Fenugreek


 
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How to Cite this Article
Pubmed Style

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri. Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants. J Complement Med Res. 2012; 1(1): 19-24. doi:10.5455/jice.20120227104636


Web Style

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri. Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants. http://www.jocmr.com/?mno=14103 [Access: November 15, 2018]. doi:10.5455/jice.20120227104636


AMA (American Medical Association) Style

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri. Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants. J Complement Med Res. 2012; 1(1): 19-24. doi:10.5455/jice.20120227104636



Vancouver/ICMJE Style

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri. Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants. J Complement Med Res. (2012), [cited November 15, 2018]; 1(1): 19-24. doi:10.5455/jice.20120227104636



Harvard Style

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri (2012) Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants. J Complement Med Res, 1 (1), 19-24. doi:10.5455/jice.20120227104636



Turabian Style

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri. 2012. Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants. Journal of Complementary Medicine Research, 1 (1), 19-24. doi:10.5455/jice.20120227104636



Chicago Style

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri. "Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants." Journal of Complementary Medicine Research 1 (2012), 19-24. doi:10.5455/jice.20120227104636



MLA (The Modern Language Association) Style

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri. "Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants." Journal of Complementary Medicine Research 1.1 (2012), 19-24. Print. doi:10.5455/jice.20120227104636



APA (American Psychological Association) Style

Fariba Sharififar, Payam Khazaeli, Narguess Alli, Elham Talebian, Raheleh Zarehshahi, Shivasadat Amiri (2012) Study of antinociceptive and anti-inflammatory activities of certain Iranian medicinal plants. Journal of Complementary Medicine Research, 1 (1), 19-24. doi:10.5455/jice.20120227104636





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