E-ISSN 2577-5669
 

Research Article 


The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy

Gholamreza Bahoush, Masoumeh Jafari, Borna Arfaie.

Abstract
Background: One of the major complications of venous access ports placement especially in cancer patients scheduling for chemotherapy is infection. We aimed to investigate the frequency of catheter-related bloodstream infections (CRBSI) originated from chemotherapy catheter in children undergoing chemotherapy.
Methods: All cancer patients referred to the Hematology department at Ali Asghar Pediatric Hospital during 2006 to 2016 who underwent chemoport treatment were included into this retrospective cross-sectional study. CRBSI was considered is children with a portal chemotherapy with at least one positive blood culture obtained from a peripheral vein and catheter tip, clinical manifestations of infections, and no apparent source for the this infection, except the catheter.
Results: Overall, 36.42% of the subjects had chemotherapy port and 63.58% had no chemotherapy port. In total, 18.87% of all patients had blood infection and 81.13% had no infection. The rate of chemotherapy catheter insertion was strongly associated with higher rate of positive blood culture for infection (p < 0.001). In this regard, the rate of infection in the children with and without catheter was reported to be 64.9% and 29.8% respectively (p < 0.001). The most common bacterial strain discovered by blood culture in both groups with and without catheter was micrococcus subfamily. Regarding clinical outcome in those subgroups of children with and without chemotherapy port, the death rate was found to be 2.7% and 0.5% respectively with no difference (p > 0.05).
Conclusion: CRBSI is a common event in children suffering chemotherapy especially in higher ages.

Key words: Chemotherapy, CRBSI, Childhood cancer, Bacterial infections.


 
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How to Cite this Article
Pubmed Style

Gholamreza Bahoush , Masoumeh Jafari , Borna Arfaie. The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy. J Complement Med Res. 2020; 11(5): 173-177.


Web Style

Gholamreza Bahoush , Masoumeh Jafari , Borna Arfaie. The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy. http://www.jocmr.com/?mno=68465 [Access: March 28, 2021].


AMA (American Medical Association) Style

Gholamreza Bahoush , Masoumeh Jafari , Borna Arfaie. The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy. J Complement Med Res. 2020; 11(5): 173-177.



Vancouver/ICMJE Style

Gholamreza Bahoush , Masoumeh Jafari , Borna Arfaie. The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy. J Complement Med Res. (2020), [cited March 28, 2021]; 11(5): 173-177.



Harvard Style

Gholamreza Bahoush , Masoumeh Jafari , Borna Arfaie (2020) The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy. J Complement Med Res, 11 (5), 173-177.



Turabian Style

Gholamreza Bahoush , Masoumeh Jafari , Borna Arfaie. 2020. The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy. Journal of Complementary Medicine Research, 11 (5), 173-177.



Chicago Style

Gholamreza Bahoush , Masoumeh Jafari , Borna Arfaie. "The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy." Journal of Complementary Medicine Research 11 (2020), 173-177.



MLA (The Modern Language Association) Style

Gholamreza Bahoush , Masoumeh Jafari , Borna Arfaie. "The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy." Journal of Complementary Medicine Research 11.5 (2020), 173-177. Print.



APA (American Psychological Association) Style

Gholamreza Bahoush , Masoumeh Jafari , Borna Arfaie (2020) The prevalence and main determinants of catheter-related bloodstream infections in children undergoing chemotherapy. Journal of Complementary Medicine Research, 11 (5), 173-177.